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Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in Ankylosing Spondylitis
CD4 helper T cells producing the pro-inflammatory cytokine IL17 (Th17) have been implicated in a number of inflammatory arthritides including the Spondyloarthritides. Th17 development is promoted by IL23. Ankylosing Spondylitis (AS), the commonest Spondyloarthritis, is genetically associated with bo...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210561/ https://ncbi.nlm.nih.gov/pubmed/21248258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002653 |
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