Activation‐Induced Killer Cell Immunoglobulin‐like Receptor 3DL2 Binding to HLA–B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis

OBJECTIVE: In the spondyloarthritides (SpA), increased numbers of CD4+ T cells express killer cell immunoglobulin‐like receptor 3DL2 (KIR‐3DL2). The aim of this study was to determine the factors that induce KIR‐3DL2 expression, and to characterize the relationship between HLA–B27 and the phenotype...

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發表在:Arthritis Rheumatol
Main Authors: Ridley, Anna, Hatano, Hiroko, Wong‐Baeza, Isabel, Shaw, Jacqueline, Matthews, Katherine K., Al‐Mossawi, Hussein, Ladell, Kristin, Price, David A., Bowness, Paul, Kollnberger, Simon
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
主題:
Spondyloarthritis
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855641/
https://ncbi.nlm.nih.gov/pubmed/26841353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39515
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