Searching for cognitive enhancement in the Morris water maze: better and worse performance in D‐amino acid oxidase knockout (Dao (−/−)) mice

A common strategy when searching for cognitive‐enhancing drugs has been to target the N‐methyl‐d‐aspartate receptor (NMDAR), given its putative role in synaptic plasticity and learning. Evidence in favour of this approach has come primarily from studies with rodents using behavioural assays like the...

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Detalhes bibliográficos
Publicado no:Eur J Neurosci
Main Authors: Pritchett, David, Taylor, Amy M, Barkus, Christopher, Engle, Sandra J, Brandon, Nicholas J, Sharp, Trevor, Foster, Russell G, Harrison, Paul J, Peirson, Stuart N, Bannerman, David M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Cognitive Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855640/
https://ncbi.nlm.nih.gov/pubmed/26833794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.13192
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