d‐amino acid oxidase knockout (Dao (−/−)) mice show enhanced short‐term memory performance and heightened anxiety, but no sleep or circadian rhythm disruption

d‐amino acid oxidase (DAO, DAAO) is an enzyme that degrades d‐serine, the primary endogenous co‐agonist of the synaptic N‐methyl‐d‐aspartate receptor. Convergent evidence implicates DAO in the pathophysiology and potential treatment of schizophrenia. To better understand the functional role of DAO,...

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Dettagli Bibliografici
Pubblicato in:Eur J Neurosci
Autori principali: Pritchett, David, Hasan, Sibah, Tam, Shu K. E., Engle, Sandra J., Brandon, Nicholas J., Sharp, Trevor, Foster, Russell G., Harrison, Paul J., Bannerman, David M., Peirson, Stuart N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
Soggetti:
Behavioral Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744680/
https://ncbi.nlm.nih.gov/pubmed/25816902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12880
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