d‐amino acid oxidase knockout (Dao (−/−)) mice show enhanced short‐term memory performance and heightened anxiety, but no sleep or circadian rhythm disruption

d‐amino acid oxidase (DAO, DAAO) is an enzyme that degrades d‐serine, the primary endogenous co‐agonist of the synaptic N‐methyl‐d‐aspartate receptor. Convergent evidence implicates DAO in the pathophysiology and potential treatment of schizophrenia. To better understand the functional role of DAO,...

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Detalhes bibliográficos
Publicado no:Eur J Neurosci
Main Authors: Pritchett, David, Hasan, Sibah, Tam, Shu K. E., Engle, Sandra J., Brandon, Nicholas J., Sharp, Trevor, Foster, Russell G., Harrison, Paul J., Bannerman, David M., Peirson, Stuart N.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Behavioral Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744680/
https://ncbi.nlm.nih.gov/pubmed/25816902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12880
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