Deletion of Metabotropic Glutamate Receptors 2 and 3 (mGlu2 & mGlu3) in Mice Disrupts Sleep and Wheel-Running Activity, and Increases the Sensitivity of the Circadian System to Light

Sleep and/or circadian rhythm disruption (SCRD) is seen in up to 80% of schizophrenia patients. The co-morbidity of schizophrenia and SCRD may in part stem from dysfunction in common brain mechanisms, which include the glutamate system, and in particular, the group II metabotropic glutamate receptor...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pritchett, David, Jagannath, Aarti, Brown, Laurence A., Tam, Shu K. E., Hasan, Sibah, Gatti, Silvia, Harrison, Paul J., Bannerman, David M., Foster, Russell G., Peirson, Stuart N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423919/
https://ncbi.nlm.nih.gov/pubmed/25950516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125523
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