Cross-species translation of the Morris maze for Alzheimer’s disease

Analogous behavioral assays are needed across animal models and human patients to improve translational research. Here, we examined the extent to which performance in the Morris water maze — the most frequently used behavioral assay of spatial learning and memory in rodents — translates to humans. W...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Possin, Katherine L., Sanchez, Pascal E., Anderson-Bergman, Clifford, Fernandez, Roland, Kerchner, Geoffrey A., Johnson, Erica T., Davis, Allyson, Lo, Iris, Bott, Nicholas T., Kiely, Thomas, Fenesy, Michelle C., Miller, Bruce L., Kramer, Joel H., Finkbeiner, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731157/
https://ncbi.nlm.nih.gov/pubmed/26784542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78464
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