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Whole organism transcriptome analysis of zebrafish models of Bardet-Biedl Syndrome and Alström Syndrome provides mechanistic insight into shared and divergent phenotypes

BACKGROUND: Bardet-Biedl Syndrome (BBS) and Alström Syndrome are two pleiotropic ciliopathies with significant phenotypic overlap between them across many tissues. Although BBS and Alström genes are necessary for the proper function of primary cilia, their role in defects across multiple organ syste...

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Pubblicato in:BMC Genomics
Autori principali: Hostelley, Timothy L., Lodh, Sukanya, Zaghloul, Norann A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855444/
https://ncbi.nlm.nih.gov/pubmed/27142762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2679-1
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