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Differential effects on β-cell mass by disruption of Bardet–Biedl syndrome or Alstrom syndrome genes

Rare genetic syndromes characterized by early-onset type 2 diabetes have revealed the importance of pancreatic β-cells in genetic susceptibility to diabetes. However, the role of genetic regulation of β-cells in disorders that are also characterized by highly penetrant obesity, a major additional ri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Mol Genet
Hauptverfasser: Lodh, Sukanya, Hostelley, Timothy L., Leitch, Carmen C., O'Hare, Elizabeth A., Zaghloul, Norann A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690491/
https://ncbi.nlm.nih.gov/pubmed/26494903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv447
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