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Differential effects on β-cell mass by disruption of Bardet–Biedl syndrome or Alstrom syndrome genes
Rare genetic syndromes characterized by early-onset type 2 diabetes have revealed the importance of pancreatic β-cells in genetic susceptibility to diabetes. However, the role of genetic regulation of β-cells in disorders that are also characterized by highly penetrant obesity, a major additional ri...
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Veröffentlicht in: | Hum Mol Genet |
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Hauptverfasser: | , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Oxford University Press
2016
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4690491/ https://ncbi.nlm.nih.gov/pubmed/26494903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv447 |
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