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Whole organism transcriptome analysis of zebrafish models of Bardet-Biedl Syndrome and Alström Syndrome provides mechanistic insight into shared and divergent phenotypes

BACKGROUND: Bardet-Biedl Syndrome (BBS) and Alström Syndrome are two pleiotropic ciliopathies with significant phenotypic overlap between them across many tissues. Although BBS and Alström genes are necessary for the proper function of primary cilia, their role in defects across multiple organ syste...

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Bibliografiska uppgifter
I publikationen:BMC Genomics
Huvudupphovsmän: Hostelley, Timothy L., Lodh, Sukanya, Zaghloul, Norann A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855444/
https://ncbi.nlm.nih.gov/pubmed/27142762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2679-1
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