Microfluidic Emulation of Mechanical Circulatory Support Device Shear-Mediated Platelet Activation

Thrombosis of ventricular assist devices (VADs) compromises their performance, with associated risks of systemic embolization, stroke, pump stop and possible death. Anti-thrombotic (AT) drugs, utilized to limit thrombosis, are largely dosed empirically, with limited testing of their efficacy. Furthe...

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Pubblicato in:Biomed Microdevices
Autori principali: Dimasi, A., Rasponi, M., Sheriff, J., Chiu, W.-C., Bluestein, D., Tran, P.L., Slepian, M. J., Redaelli, A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855287/
https://ncbi.nlm.nih.gov/pubmed/26578003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10544-015-0015-1
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