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The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP(3) pathway

The ability of radial glial progenitors (RGPs) to generate cortical neurons is determined by local extracellular factors and signaling pathways intrinsic to RGPs. Here we find that GPR157, an orphan G protein-coupled receptor, localizes to RGPs’ primary cilia exposed to the cerebrospinal fluid (CSF)...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Takeo, Yutaka, Kurabayashi, Nobuhiro, Nguyen, Minh Dang, Sanada, Kamon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855140/
https://ncbi.nlm.nih.gov/pubmed/27142930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25180
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