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DYRK1A overexpression enhances STAT activity and astrogliogenesis in a Down syndrome mouse model

Down syndrome (DS) arises from triplication of genes on human chromosome 21 and is associated with anomalies in brain development such as reduced production of neurons and increased generation of astrocytes. Here, we show that differentiation of cortical progenitor cells into astrocytes is promoted...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO Rep
Egile Nagusiak: Kurabayashi, Nobuhiro, Nguyen, Minh Dang, Sanada, Kamon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley & Sons, Ltd 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641506/
https://ncbi.nlm.nih.gov/pubmed/26373433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540374
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