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DYRK1A overexpression enhances STAT activity and astrogliogenesis in a Down syndrome mouse model
Down syndrome (DS) arises from triplication of genes on human chromosome 21 and is associated with anomalies in brain development such as reduced production of neurons and increased generation of astrocytes. Here, we show that differentiation of cortical progenitor cells into astrocytes is promoted...
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| Publicado no: | EMBO Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4641506/ https://ncbi.nlm.nih.gov/pubmed/26373433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540374 |
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