Neuroprotective Role of the Basic Leucine Zipper Transcription Factor NFIL3 in Models of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of motor neurons. Here we show that the basic leucine zipper transcription factor NFIL3 (also called E4BP4) confers neuroprotection in models of ALS. NFIL3 is up-regulated in primary neurons challenged with...

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Библиографические подробности
Главные авторы: Tamai, So-ichi, Imaizumi, Keisuke, Kurabayashi, Nobuhiro, Nguyen, Minh Dang, Abe, Takaya, Inoue, Masatoshi, Fukada, Yoshitaka, Sanada, Kamon
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
Предметы:
Neurobiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894342/
https://ncbi.nlm.nih.gov/pubmed/24280221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.524389
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