Caspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasion

In addition to their role in programmed cell death, caspases exert non-lethal functions in diverse developmental processes including cell differentiation or tissue remodeling. Terminal cell cycle exit and differentiation can be promoted by increased level of the CDK inhibitor p27(Kip1). Activated ca...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncogene
Egile Nagusiak: Podmirseg, S R, Jäkel, H, Ranches, G D, Kullmann, M K, Sohm, B, Villunger, A, Lindner, H, Hengst, L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854979/
https://ncbi.nlm.nih.gov/pubmed/26829051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.524
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