Caspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasion

In addition to their role in programmed cell death, caspases exert non-lethal functions in diverse developmental processes including cell differentiation or tissue remodeling. Terminal cell cycle exit and differentiation can be promoted by increased level of the CDK inhibitor p27(Kip1). Activated ca...

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Detaylı Bibliyografya
Yayımlandı:Oncogene
Asıl Yazarlar: Podmirseg, S R, Jäkel, H, Ranches, G D, Kullmann, M K, Sohm, B, Villunger, A, Lindner, H, Hengst, L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854979/
https://ncbi.nlm.nih.gov/pubmed/26829051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.524
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