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The CDK inhibitor p57(Kip2) enhances the activity of the transcriptional coactivator FHL2

The eukaryotic cell cycle is negatively regulated by cyclin-dependent kinase inhibitors (CKIs). p57(Kip2) is a member of the Cip/Kip family of CKIs and frequently inactivated by genomic mutations associated with human overgrowth disorders. There is increasing evidence for p57 to control cellular pro...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kullmann, Michael Keith, Podmirseg, Silvio Roland, Roilo, Martina, Hengst, Ludger
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188849/
https://ncbi.nlm.nih.gov/pubmed/32346031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62641-4
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