B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6

Dysregulated germinal center (GC) responses are implicated in the pathogenesis of human autoimmune diseases, including systemic lupus erythematosus (SLE). Although both type 1 and type 2 interferons (IFNs) are involved in lupus pathogenesis, their respective impacts on the establishment of autoimmun...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Jackson, Shaun W., Jacobs, Holly M., Arkatkar, Tanvi, Dam, Elizabeth M., Scharping, Nicole E., Kolhatkar, Nikita S., Hou, Baidong, Buckner, Jane H., Rawlings, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854732/
https://ncbi.nlm.nih.gov/pubmed/27069113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151724
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