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Structural analysis of the spliceosomal RNA helicase Prp28 from the thermophilic eukaryote Chaetomium thermophilum

Prp28 (pre-mRNA-splicing ATP-dependent RNA helicase 28) is a spliceosomal DEAD-box helicase which is involved in two steps of spliceosome assembly. It is required for the formation of commitment complex 2 in an ATP-independent manner as well as for the formation of the pre-catalytic spliceosome, whi...

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Veröffentlicht in:Acta Crystallogr F Struct Biol Commun
Hauptverfasser: Tauchert, Marcel J., Ficner, Ralf
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854570/
https://ncbi.nlm.nih.gov/pubmed/27139834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16006038
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