Low Protective Efficacy of the Current Japanese Encephalitis Vaccine against the Emerging Genotype 5 Japanese Encephalitis Virus

BACKGROUND: The current Japanese encephalitis (JE) vaccine derived from G3 JE virus (JEV) can induce protective immunity against G1–G4 JEV genotypes. However, protective efficacy against the emerging G5 genotype has not been reported. METHODS/PRINCIPAL FINDINGS: Using in vitro and in vivo tests, bio...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Negl Trop Dis
Main Authors: Cao, Lei, Fu, Shihong, Gao, Xiaoyan, Li, Minghua, Cui, Shiheng, Li, Xiaolong, Cao, Yuxi, Lei, Wenwen, Lu, Zhi, He, Ying, Wang, Huanyu, Yan, Jinghua, Gao, George Fu, Liang, Guodong
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854478/
https://ncbi.nlm.nih.gov/pubmed/27139722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004686
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