Low Protective Efficacy of the Current Japanese Encephalitis Vaccine against the Emerging Genotype 5 Japanese Encephalitis Virus

BACKGROUND: The current Japanese encephalitis (JE) vaccine derived from G3 JE virus (JEV) can induce protective immunity against G1–G4 JEV genotypes. However, protective efficacy against the emerging G5 genotype has not been reported. METHODS/PRINCIPAL FINDINGS: Using in vitro and in vivo tests, bio...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Negl Trop Dis
Päätekijät: Cao, Lei, Fu, Shihong, Gao, Xiaoyan, Li, Minghua, Cui, Shiheng, Li, Xiaolong, Cao, Yuxi, Lei, Wenwen, Lu, Zhi, He, Ying, Wang, Huanyu, Yan, Jinghua, Gao, George Fu, Liang, Guodong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854478/
https://ncbi.nlm.nih.gov/pubmed/27139722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004686
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