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Functional and Structural Mimicry of Cellular Protein Kinase A Anchoring Proteins by a Viral Oncoprotein

The oncoproteins of the small DNA tumor viruses interact with a plethora of cellular regulators to commandeer control of the infected cell. During infection, adenovirus E1A deregulates cAMP signalling and repurposes it for activation of viral gene expression. We show that E1A structurally and functi...

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發表在:PLoS Pathog
Main Authors: King, Cason R., Cohen, Michael J., Fonseca, Gregory J., Dirk, Brennan S., Dikeakos, Jimmy D., Mymryk, Joe S.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854477/
https://ncbi.nlm.nih.gov/pubmed/27137912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005621
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