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The adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2

DYRK1A is a constitutively active protein kinase that has a critical role in growth and development which functions by regulating cell proliferation, differentiation and survival. DCAF7 (also termed WDR68 or HAN11) is a cellular binding partner of DYRK1A and also regulates signalling by the protein...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Glenewinkel, Florian, Cohen, Michael J., King, Cason R., Kaspar, Sophie, Bamberg-Lemper, Simone, Mymryk, Joe S., Becker, Walter
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910162/
https://ncbi.nlm.nih.gov/pubmed/27307198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28241
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