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Functional and Structural Mimicry of Cellular Protein Kinase A Anchoring Proteins by a Viral Oncoprotein

The oncoproteins of the small DNA tumor viruses interact with a plethora of cellular regulators to commandeer control of the infected cell. During infection, adenovirus E1A deregulates cAMP signalling and repurposes it for activation of viral gene expression. We show that E1A structurally and functi...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: King, Cason R., Cohen, Michael J., Fonseca, Gregory J., Dirk, Brennan S., Dikeakos, Jimmy D., Mymryk, Joe S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854477/
https://ncbi.nlm.nih.gov/pubmed/27137912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005621
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