Integrative genomic deconvolution of rheumatoid arthritis GWAS loci into gene and cell type associations

BACKGROUND: Although genome-wide association studies (GWAS) have identified over 100 genetic loci associated with rheumatoid arthritis (RA), our ability to translate these results into disease understanding and novel therapeutics is limited. Most RA GWAS loci reside outside of protein-coding regions...

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發表在:Genome Biol
Main Authors: Walsh, Alice M., Whitaker, John W., Huang, C. Chris, Cherkas, Yauheniya, Lamberth, Sarah L., Brodmerkel, Carrie, Curran, Mark E., Dobrin, Radu
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853861/
https://ncbi.nlm.nih.gov/pubmed/27140173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0948-6
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