An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination

Remyelination is the generation of new myelin sheaths after injury facilitated by processes of differentiating oligodendrocyte precursor cells (OPCs). Although this repair phenomenon occurs in lesions of multiple sclerosis patients, many lesions fail to completely remyelinate. A number of factors ha...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Keough, Michael B., Rogers, James A., Zhang, Ping, Jensen, Samuel K., Stephenson, Erin L., Chen, Tieyu, Hurlbert, Mitchel G., Lau, Lorraine W., Rawji, Khalil S., Plemel, Jason R., Koch, Marcus, Ling, Chang-Chun, Yong, V. Wee
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853428/
https://ncbi.nlm.nih.gov/pubmed/27115988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11312
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