Targeting the Chondroitin Sulfate Proteoglycans: Evaluating Fluorinated Glucosamines and Xylosides in Screens Pertinent to Multiple Sclerosis

[Image: see text] Chondroitin sulfate proteoglycans (CSPGs) are upregulated in insults to the central nervous system, including multiple sclerosis (MS), an inflammatory demyelinating condition of the central nervous system. CSPGs appear to be detrimental in MS, as they enhance immune responses and a...

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Udgivet i:ACS Cent Sci
Main Authors: Stephenson, Erin L., Zhang, Ping, Ghorbani, Samira, Wang, Aixia, Gu, Jiamin, Keough, Michael B., Rawji, Khalil Sherali, Silva, Claudia, Yong, V. Wee, Ling, Chang-Chun
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2019
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661872/
https://ncbi.nlm.nih.gov/pubmed/31404231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.9b00327
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