An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination

Remyelination is the generation of new myelin sheaths after injury facilitated by processes of differentiating oligodendrocyte precursor cells (OPCs). Although this repair phenomenon occurs in lesions of multiple sclerosis patients, many lesions fail to completely remyelinate. A number of factors ha...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Keough, Michael B., Rogers, James A., Zhang, Ping, Jensen, Samuel K., Stephenson, Erin L., Chen, Tieyu, Hurlbert, Mitchel G., Lau, Lorraine W., Rawji, Khalil S., Plemel, Jason R., Koch, Marcus, Ling, Chang-Chun, Yong, V. Wee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853428/
https://ncbi.nlm.nih.gov/pubmed/27115988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11312
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