An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination

Remyelination is the generation of new myelin sheaths after injury facilitated by processes of differentiating oligodendrocyte precursor cells (OPCs). Although this repair phenomenon occurs in lesions of multiple sclerosis patients, many lesions fail to completely remyelinate. A number of factors ha...

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Publicat a:Nat Commun
Autors principals: Keough, Michael B., Rogers, James A., Zhang, Ping, Jensen, Samuel K., Stephenson, Erin L., Chen, Tieyu, Hurlbert, Mitchel G., Lau, Lorraine W., Rawji, Khalil S., Plemel, Jason R., Koch, Marcus, Ling, Chang-Chun, Yong, V. Wee
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853428/
https://ncbi.nlm.nih.gov/pubmed/27115988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11312
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