Efflux Pump Blockers in Gram-Negative Bacteria: The New Generation of Hydantoin Based-Modulators to Improve Antibiotic Activity

Multidrug resistant (MDR) bacteria are an increasing health problem with the shortage of new active antibiotic agents. Among effective mechanisms that contribute to the spread of MDR Gram-negative bacteria are drug efflux pumps that expel clinically important antibiotic classes out of the cell. Drug...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Otręebska-Machaj, Ewa, Chevalier, Jacqueline, Handzlik, Jadwiga, Szymańska, Ewa, Schabikowski, Jakub, Boyer, Gérard, Bolla, Jean-Michel, Kieć-Kononowicz, Katarzyna, Pagès, Jean-Marie, Alibert, Sandrine
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853399/
https://ncbi.nlm.nih.gov/pubmed/27199950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00622
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