Tricyclic xanthine derivatives containing a basic substituent: adenosine receptor affinity and drug-related properties

A library of 27 novel amide derivatives of annelated xanthines was designed and synthesized. The new compounds represent 1,3-dipropyl- and 1,3-dibutyl-pyrimido[2,1-f]purinedione-9-ethylphenoxy derivatives including a CH(2)CONH linker between the (CH(2))(2)-amino group and the phenoxy moiety. A synth...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Medchemcomm
Asıl Yazarlar: Załuski, Michał, Stanuch, Katarzyna, Karcz, Tadeusz, Hinz, Sonja, Latacz, Gniewomir, Szymańska, Ewa, Schabikowski, Jakub, Doroż-Płonka, Agata, Handzlik, Jadwiga, Drabczyńska, Anna, Müller, Christa E., Kieć-Kononowicz, Katarzyna
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Royal Society of Chemistry 2018
Konular:
Chemistry
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071793/
https://ncbi.nlm.nih.gov/pubmed/30108984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00070k
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller