Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells

The methylcytosine dioxygenases TET proteins (TET1, TET2, and TET3) play important regulatory roles in neural function. In this study, we investigated the role of TET proteins in neuronal differentiation using Neuro2a cells as a model. We observed that knockdown of TET1, TET2 or TET3 promoted neuron...

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Veröffentlicht in:Protein Cell
Hauptverfasser: Gao, Jie, Ma, Yue, Fu, Hua-Lin, Luo, Qian, Wang, Zhen, Xiao, Yu-Huan, Yang, Hao, Cui, Da-Xiang, Jin, Wei-Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Higher Education Press 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853314/
https://ncbi.nlm.nih.gov/pubmed/27113584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-016-0267-4
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