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Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells

The methylcytosine dioxygenases TET proteins (TET1, TET2, and TET3) play important regulatory roles in neural function. In this study, we investigated the role of TET proteins in neuronal differentiation using Neuro2a cells as a model. We observed that knockdown of TET1, TET2 or TET3 promoted neuron...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Gao, Jie, Ma, Yue, Fu, Hua-Lin, Luo, Qian, Wang, Zhen, Xiao, Yu-Huan, Yang, Hao, Cui, Da-Xiang, Jin, Wei-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853314/
https://ncbi.nlm.nih.gov/pubmed/27113584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-016-0267-4
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