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The F-BAR domain of srGAP2 induces membrane protrusions required for neuronal migration and morphogenesis

During brain development, proper neuronal migration and morphogenesis is critical for the establishment of functional neural circuits. Here we report that srGAP2 negatively regulates neuronal migration and induces neurite outgrowth and branching through the ability of its F-BAR domain to induce filo...

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Detalhes bibliográficos
Main Authors: Guerrier, Sabrice, Coutinho-Budd, Jaeda, Sassa, Takayuki, Gresset, Aurélie, Jordan, Nicole Vincent, Cheng, Ken, Jin, Wei-Lin, Frost, Adam, Polleux, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797480/
https://ncbi.nlm.nih.gov/pubmed/19737524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.06.047
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