Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation

Structural genomic variations represent a major driving force of evolution and a burst of large segmental gene duplications occurred in the human lineage during its separation from non-human primates. SRGAP2, a gene recently implicated in neocortical development, has undergone two human-specific dup...

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Detalhes bibliográficos
Main Authors: Charrier, Cécile, Joshi, Kaumudi, Coutinho-Budd, Jaeda, Kim, Ji-Eun, Lambert, Nelle, de Marchena, Jacqueline, Jin, Wei-Lin, Vanderhaeghen, Pierre, Ghosh, Anirvan, Sassa, Takayuki, Polleux, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357949/
https://ncbi.nlm.nih.gov/pubmed/22559944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.03.034
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