Melanoma-induced suppression of tumor antigen-specific T cell expansion is comparable to suppression of global T cell expansion

We have observed that in vivo interaction between melanoma and resting T cells promotes suppression of antigen-driven proliferative T cell expansion. We hypothesized that this suppression would affect tumor antigen-specific T cell populations more potently than tumor-unrelated T cell populations. A...

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Publicado no:Cell Immunol
Main Authors: Russ, Andrew J., Xu, Kyle, Wentworth, Lucy, Alam, Sheeba, Meyers, Justin V., Macklin, Michael D., Rakhmilevich, Alexander L., Rajamanickam, Victoria, Suresh, M., Cho, Clifford S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852956/
https://ncbi.nlm.nih.gov/pubmed/21741629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2011.06.011
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