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Rapid Expansion of Highly Functional Antigen-Specific T cells from Melanoma Patients by Nanoscale Artificial Antigen Presenting Cells

PURPOSE: Generation of antigen-specific T cells from cancer patients employs large numbers of peripheral blood cells and/or tumor infiltrating cells to generate antigen-presenting and effector cells commonly requiring multiple rounds of re-stimulation ex vivo. We used a novel paramagnetic, nanoparti...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Ichikawa, Junya, Yoshida, Tatsuya, Isser, Ariel Y., Laino, Andressa S., Vassallo, Melinda, Woods, David M., Kim, Sojung, Oelke, Mathias, Jones, Kristi, Schneck, Jonathan P., Weber, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334099/
https://ncbi.nlm.nih.gov/pubmed/32241816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-3487
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