Slow Replication Fork Velocity of Homologous Recombination-Defective Cells Results from Endogenous Oxidative Stress

Replications forks are routinely hindered by different endogenous stresses. Because homologous recombination plays a pivotal role in the reactivation of arrested replication forks, defects in homologous recombination reveal the initial endogenous stress(es). Homologous recombination-defective cells...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Wilhelm, Therese, Ragu, Sandrine, Magdalou, Indiana, Machon, Christelle, Dardillac, Elodie, Técher, Hervé, Guitton, Jérôme, Debatisse, Michelle, Lopez, Bernard S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852921/
https://ncbi.nlm.nih.gov/pubmed/27135742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006007
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