Loading...

Methods for Efficient Elimination of Mitochondrial DNA from Cultured Cells

Here, we document that persistent mitochondria DNA (mtDNA) damage due to mitochondrial overexpression of the Y147A mutant uracil-N-glycosylase as well as mitochondrial overexpression of bacterial Exonuclease III or Herpes Simplex Virus protein UL12.5M185 can induce a complete loss of mtDNA (ρ(0) phe...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Spadafora, Domenico, Kozhukhar, Nataliya, Chouljenko, Vladimir N., Kousoulas, Konstantin G., Alexeyev, Mikhail F.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852919/
https://ncbi.nlm.nih.gov/pubmed/27136098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154684
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!