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Cullin 3 Ubiquitin Ligases in Cancer Biology: Functions and Therapeutic Implications

Cullin-RING ubiquitin ligases are the largest E3 ligase family in eukaryotes and are multiprotein complexes. In these complexes, the Cullin protein serves as a scaffold to connect two functional modules of the ligases, the catalytic subunit and substrate-binding subunit. To date, eight members of th...

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Bibliografische gegevens
Gepubliceerd in:Front Oncol
Hoofdauteurs: Chen, Hsin-Yi, Chen, Ruey-Hwa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852199/
https://ncbi.nlm.nih.gov/pubmed/27200299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00113
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