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Intratumoral heterogeneity of the epigenome

Investigation into intratumoral heterogeneity (ITH) of the epigenome is in a formative stage. The patterns of tumor evolution inferred from epigenetic ITH and genetic ITH are remarkably similar, suggesting widespread co-dependency of these disparate mechanisms. The biological and clinical relevance...

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Publicat a:Cancer Cell
Autors principals: Mazor, Tali, Pankov, Aleksandr, Song, Jun S., Costello, Joseph F.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852161/
https://ncbi.nlm.nih.gov/pubmed/27070699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.03.009
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