Multiplatform Molecular Profiling Reveals Epigenomic Intratumor Heterogeneity in Ependymoma

Ependymomas exist within distinct genetic subgroups, but the molecular diversity within individual ependymomas is unknown. We perform multiplatform molecular profiling of 6 spatially distinct samples from an ependymoma with C11orf95-RELA fusion. DNA methylation and RNA sequencing distinguish cluster...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Liu, S. John, Magill, Stephen T., Vasudevan, Harish N., Hilz, Stephanie, Villanueva-Meyer, Javier E., Lastella, Sydney, Daggubati, Vikas, Spatz, Jordan, Choudhury, Abrar, Orr, Brent A., Demaree, Benjamin, Seo, Kyounghee, Ferris, Sean P., Abate, Adam R., Oberheim Bush, Nancy Ann, Bollen, Andrew W., McDermott, Michael W., Costello, Joseph F., Raleigh, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7313374/
https://ncbi.nlm.nih.gov/pubmed/32023450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.01.018
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