Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma

Meningiomas are the most common primary intracranial tumors, but the molecular drivers of meningioma tumorigenesis are poorly understood. We hypothesized that investigating intratumor heterogeneity in meningiomas would elucidate biologic drivers and reveal new targets for molecular therapy. To test...

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Publicado no:Nat Commun
Main Authors: Magill, Stephen T., Vasudevan, Harish N., Seo, Kyounghee, Villanueva-Meyer, Javier E., Choudhury, Abrar, John Liu, S., Pekmezci, Melike, Findakly, Sarah, Hilz, Stephanie, Lastella, Sydney, Demaree, Benjamin, Braunstein, Steve E., Bush, Nancy Ann Oberheim, Aghi, Manish K., Theodosopoulos, Philip V., Sneed, Penny K., Abate, Adam R., Berger, Mitchel S., McDermott, Michael W., Lim, Daniel A., Ullian, Erik M., Costello, Joseph F., Raleigh, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511976/
https://ncbi.nlm.nih.gov/pubmed/32968068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18582-7
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