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Histone modifiers and marks define heterogeneous groups of colorectal carcinomas and affect responses to HDAC inhibitors in vitro

Little is known about histone modifiers and histone marks in colorectal cancers (CRC). The present study therefore addressed the role of histone acetylation and histone deacetylases (HDAC) in CRCs in situ and in vitro. Immunohistochemistry of primary CRCs (n=47) revealed that selected histone marks...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Lutz, Lisa, Fitzner, Ingrid Coutiño, Ahrens, Theresa, Geißler, Anna-Lena, Makowiec, Frank, Hopt, Ulrich T, Bogatyreva, Lioudmila, Hauschke, Dieter, Werner, Martin, Lassmann, Silke
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851845/
https://ncbi.nlm.nih.gov/pubmed/27152243
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