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ATM mutations and E-cadherin expression define sensitivity to EGFR-targeted therapy in colorectal cancer
EGFR-targeted therapy is a key treatment approach in patients with RAS wildtype metastatic colorectal cancers (CRC). Still, also RAS wildtype CRC may be resistant to EGFR-targeted therapy, with few predictive markers available for improved stratification of patients. Here, we investigated response o...
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| Izdano u: | Oncotarget |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Impact Journals LLC
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5370031/ https://ncbi.nlm.nih.gov/pubmed/28199979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15211 |
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