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Lipid Rafts Assemble Dynein Ensembles

New work by Rai et al. identifies a novel mechanism regulating phagosome transport in cells: the clustering of dynein motors into lipid microdomains, leading to enhanced unidirectional motility. Clustering may be especially important for dynein, a motor that works most efficiently in teams.

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Trends Biochem Sci
Prif Awduron: Nirschl, Jeffrey J., Ghiretti, Amy E., Holzbaur, Erika L.F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851571/
https://ncbi.nlm.nih.gov/pubmed/27061495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2016.03.005
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