Nonhomologous end joining of complex DNA double-strand breaks with proximal thymine glycol and interplay with base excision repair

DNA double-strand breaks induced by ionizing radiation are often accompanied by ancillary oxidative base damage that may prevent or delay their repair. In order to better define the features that make some DSBs repair-resistant, XLF-dependent nonhomologous end joining of blunt-ended DSB substrates h...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Almohaini, Mohammed, Chalasani, Sri Lakshmi, Bafail, Duaa, Akopiants, Konstantin, Zhou, Tong, Yannone, Steven M., Ramsden, Dale A., Hartman, Matthew C.T., Povirk, Lawrence F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851560/
https://ncbi.nlm.nih.gov/pubmed/27049455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.03.003
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