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Patching and Single-Strand Ligation in Nonhomologous DNA End Joining Despite Persistence of a Closely Opposed 3′-Phosphoglycolate-Terminated Strand Break
Previous work showed that in human nuclear extracts, double-strand break substrates bearing partially complementary (-ACG) 3′-phosphoglycolate (PG)-terminated 3′ overhangs are joined by a mechanism involving annealing of the terminal CG dinucleotides, PG removal, single-base gap filling and ligation...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2956515/ https://ncbi.nlm.nih.gov/pubmed/20726725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR2050.1 |
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