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Patching and Single-Strand Ligation in Nonhomologous DNA End Joining Despite Persistence of a Closely Opposed 3′-Phosphoglycolate-Terminated Strand Break

Previous work showed that in human nuclear extracts, double-strand break substrates bearing partially complementary (-ACG) 3′-phosphoglycolate (PG)-terminated 3′ overhangs are joined by a mechanism involving annealing of the terminal CG dinucleotides, PG removal, single-base gap filling and ligation...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Zhou, Rui-Zhe, Akopiants, Konstantin, Povirk, Lawrence F.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956515/
https://ncbi.nlm.nih.gov/pubmed/20726725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR2050.1
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