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A continuum model of transcriptional bursting

Transcription occurs in stochastic bursts. Early models based upon RNA hybridisation studies suggest bursting dynamics arise from alternating inactive and permissive states. Here we investigate bursting mechanism in live cells by quantitative imaging of actin gene transcription, combined with molecu...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Corrigan, Adam M, Tunnacliffe, Edward, Cannon, Danielle, Chubb, Jonathan R
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850746/
https://ncbi.nlm.nih.gov/pubmed/26896676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13051
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