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A continuum model of transcriptional bursting

Transcription occurs in stochastic bursts. Early models based upon RNA hybridisation studies suggest bursting dynamics arise from alternating inactive and permissive states. Here we investigate bursting mechanism in live cells by quantitative imaging of actin gene transcription, combined with molecu...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Corrigan, Adam M, Tunnacliffe, Edward, Cannon, Danielle, Chubb, Jonathan R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850746/
https://ncbi.nlm.nih.gov/pubmed/26896676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13051
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