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Generation of Single-Cell Transcript Variability by Repression

Gene expression levels vary greatly within similar cells, even within clonal cell populations [1]. These spontaneous expression differences underlie cell fate diversity in both differentiation and disease [2]. The mechanisms responsible for generating expression variability are poorly understood. Us...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Antolović, Vlatka, Miermont, Agnes, Corrigan, Adam M., Chubb, Jonathan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483230/
https://ncbi.nlm.nih.gov/pubmed/28602650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.05.028
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