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Generation of Single-Cell Transcript Variability by Repression

Gene expression levels vary greatly within similar cells, even within clonal cell populations [1]. These spontaneous expression differences underlie cell fate diversity in both differentiation and disease [2]. The mechanisms responsible for generating expression variability are poorly understood. Us...

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Publicado en:Curr Biol
Autores principales: Antolović, Vlatka, Miermont, Agnes, Corrigan, Adam M., Chubb, Jonathan R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483230/
https://ncbi.nlm.nih.gov/pubmed/28602650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.05.028
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