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Live imaging of nascent RNA dynamics reveals distinct types of transcriptional pulse regulation

Transcription of genes can be discontinuous, occurring in pulses or bursts. It is not clear how properties of transcriptional pulses vary between different genes. We compared the pulsing of five housekeeping and five developmentally induced genes by direct imaging of single gene transcriptional even...

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Detalhes bibliográficos
Main Authors: Muramoto, Tetsuya, Cannon, Danielle, Gierliński, Marek, Corrigan, Adam, Barton, Geoffrey J., Chubb, Jonathan R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358836/
https://ncbi.nlm.nih.gov/pubmed/22529358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117603109
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